What Does modafinil Mean?
Wiki Article
Not known; not sympathomimetic; may perhaps increase dopamine stages while in the brain by binding to the dopamine transporter and inhibiting dopamine reuptake
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Retail store modafinil in a safe position in order that no one else might take it unintentionally or on purpose. Keep track of the number of tablets are remaining so you'll know if any are missing.
Prevent or substitute another drug for these medicines when achievable. Assess for loss of therapeutic impact if medication need to be coadministered. Change dose Based on prescribing info if necessary.
No particular dose adjustment recommended when tofacitinib coadministered with potent CYP2C19 inhibitors; decrease tofacitinib dose if coadministered with both average CYP3A4 and powerful CYP2C19 inhibitors .
modafinil raises amounts of eluxadoline by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. As being a precautionary measure because of incomplete info on the metabolism of eluxadoline, use caution when coadministered with powerful CYP2C19 inhibitors.
stiripentol will raise the stage or outcome of modafinil by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Carefully. Take into account cutting down the dose of CYP2C19 substrates, if adverse reactions are experienced when administered concomitantly with stiripentol.
Psychiatric Issues: Modafinil should be applied with caution in sufferers having a heritage of psychosis and/or mania. This sort of clients need to be monitored for hallucinations, delusions, mania, aggression, and suicidal ideation upon setting up modafinil. Discontinuation is suggested if these symptoms acquire.
modafinil will minimize the extent or effect of iobenguane I 131 by Other (see comment). Stay away from or Use Alternate Drug. Determined by the mechanism of action of iobenguane, medications that minimize catecholamine uptake or that deplete catecholamine merchants may well interfere with iobenguane uptake into cells, and thus, cut down iobenguane efficacy.
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modafinil will minimize the level or effect of levoketoconazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unidentified.
Insignificant (one)modafinil will boost the amount or impact of lansoprazole by influencing hepatic enzyme CYP2C19 metabolism. Small/Importance Unfamiliar. more info Net impact on pantoprazole steps unfamiliar because of opposing outcomes of CYP450 enzymes; monitor
Prescription drugs which have phase therapy linked to Just about every prescription. This restriction normally demands that selected requirements be fulfilled ahead of approval for your prescription.
rifabutin will decrease the level or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.